Heterogeneity of erythroid precursor cells. Hemoglobin quantitation in single clones by radioimmunoassay.
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Heterogeneity of erythroid precursor cells. Hemoglobin quantitation in single clones by radioimmunoassay.
Accumulation of HbF and HbA in individual erythroid clones, or bursts, grown in culture from early human erythroid progenitor cells (BFUe, erythroid burst-forming unit) was measured using sensitive and speciiic radioimmunoassays. HbF and HbA could be quantitated simultaneously in individual bursts and total hemoglobin levels as low as several hundred picograms per burst could be measured. Burst...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1981
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)69801-7